Magna Diagnostics will provide a novel PoC magnetic-bead-based lab-on-a-chip diagnostic platform called "MAZER" that is rapid, portable, easy to perform and reliable. The system will consist of a single-test “disposable” and an “analyser”.
The analyser consists of the mechanic and electronic components that control the processes on the disposable, which is a microfluidic cartridge, acquires and manages the data, and displays the final results. The micro-fluidic disposable contains appropriate reagents such as buffer solutions, enzymes and biological marker probes such as oligonucleotides or monoclonal antibodies. This microfluidic device will simplify processes involving target molecule detection as well as reduce reagent consumption through use of nanoscale technology.
Functionalized magnetic beads bind the target molecules of the sample and are transported through reaction cavities on the microfluidic cartridge. Finally the beads are detected on a CMOS-based biochip using thousands of magnetoresistive sensor elements. Although processing relative small amounts of specimen, microfluidics and nanotechnology provide sufficient results regarding sensitivity and specificity.
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